125 Episodes

  1. Matthew McConaughey

    Published: 9/18/2025

  2. Ezra Klein

    Published: 9/4/2025

  3. Andrew Callaghan

    Published: 8/21/2025

  4. Nick Swardson

    Published: 8/7/2025

  5. Leanne Morgan

    Published: 7/24/2025

  6. Earthquake

    Published: 7/10/2025

  7. Ramy Youssef

    Published: 6/26/2025

  8. Stephen Merchant

    Published: 6/12/2025

  9. Josh Groban

    Published: 5/29/2025

  10. Tom Green

    Published: 5/15/2025

  11. W. Kamau Bell

    Published: 5/1/2025

  12. Larry Wilmore

    Published: 4/17/2025

  13. Blake Griffin

    Published: 4/3/2025

  14. Carol Leifer

    Published: 3/20/2025

  15. William H. Macy

    Published: 3/6/2025

  16. Ari Shaffir

    Published: 2/20/2025

  17. Joe List

    Published: 2/6/2025

  18. Jason Reitman

    Published: 1/23/2025

  19. Paul Scheer

    Published: 1/9/2025

  20. Jerry O'Connell

    Published: 12/19/2024

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Based on his Netflix comedy special, "Blocks." Neal Brennan interviews friends and colleagues about the things that make them feel lonely, isolated, and like something's wrong - and how they are persevering despite these blocks.